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RECRUITING
NCT06582381
NA

Evaluation of Biomarkers for Predicting Macronutrient Intake

Sponsor: Texas A&M University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to establish the relationship between macronutrient food intake and the resulting blood and intersticial fluid (ISF )levels of small molecule markers, as well as, validate wearable optical readers and data fusion algorithms to accurately predict individual-specific macronutrient availability in real time. The study involves 1 screening visit of approximately 2 hours and up to 4 study days of approximately 14 hours. Subjects will be asked to arrive in the fasted state on all study days. Fasting prior to screening is not required. On the screening visit, body weight, height, and body composition by Dual-energy X-ray absorptiometry (DXA) will be measured. In addition, habitual dietary intake, physical activity level (PASE), and quality of life (SGRQ-C) will be assessed.

Key Details

Gender

All

Age Range

50 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

33

Start Date

2023-12-06

Completion Date

2026-12

Last Updated

2025-07-20

Healthy Volunteers

Yes

Interventions

OTHER

Meal set A

morning meal: low carbohydrate, low protein, low fat afternoon meal: high carbohydrate, high protein, high fat

OTHER

Meal set B

morning meal: low carbohydrate, high protien, low fat meal afternoon meal: high carbohydrate, low protein, high fat meal

OTHER

Meal set C

morning meal: low carbohydrate, low protien, low fat meal afternoon meal: high carbohydrate, high protein, low fat meal

OTHER

Meal set D

morning meal: high carbohydrate, low protien, low fat meal afternoon meal: low carbohydrate, high protein, high fat meal

Locations (1)

Center for Translational Research in Aging & Longevity

College Station, Texas, United States