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Evaluation of Biomarkers for Predicting Macronutrient Intake
Sponsor: Texas A&M University
Summary
The goal of this clinical trial is to establish the relationship between macronutrient food intake and the resulting blood and intersticial fluid (ISF )levels of small molecule markers, as well as, validate wearable optical readers and data fusion algorithms to accurately predict individual-specific macronutrient availability in real time. The study involves 1 screening visit of approximately 2 hours and up to 4 study days of approximately 14 hours. Subjects will be asked to arrive in the fasted state on all study days. Fasting prior to screening is not required. On the screening visit, body weight, height, and body composition by Dual-energy X-ray absorptiometry (DXA) will be measured. In addition, habitual dietary intake, physical activity level (PASE), and quality of life (SGRQ-C) will be assessed.
Key Details
Gender
All
Age Range
50 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
33
Start Date
2023-12-06
Completion Date
2026-12
Last Updated
2025-07-20
Healthy Volunteers
Yes
Conditions
Interventions
Meal set A
morning meal: low carbohydrate, low protein, low fat afternoon meal: high carbohydrate, high protein, high fat
Meal set B
morning meal: low carbohydrate, high protien, low fat meal afternoon meal: high carbohydrate, low protein, high fat meal
Meal set C
morning meal: low carbohydrate, low protien, low fat meal afternoon meal: high carbohydrate, high protein, low fat meal
Meal set D
morning meal: high carbohydrate, low protien, low fat meal afternoon meal: low carbohydrate, high protein, high fat meal
Locations (1)
Center for Translational Research in Aging & Longevity
College Station, Texas, United States