Clinical Research Directory

Inclusion Criteria: 1. Willing and able to give written informed consent 2. Age 18-30 years 3. Female sex assigned at birth 4. HIV-seronegative, according to national HIV testing algorithm 5. Has a current prescription for PrEP, \> 1 month, according to the national guidelines of Kenya Exclusion Criteria: 1. Pregnant 2. Breastfeeding a child 3. Allergy to tetracycline class 4. Current medications which may impact doxycycline metabolism or that are contraindicated with doxycycline, as per the prescribing information. These include systemic retinoids, barbiturates, carbamazepine, phenytoin, and warfarin. 5. Active, clinically significant medical or psychiatric conditions that would interfere with study participation, at the discretion of the site investigator or designee. 6. Prior enrollment in The dPEP Kenya Study