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RECRUITING
NCT06584448
NA

Drinking, Acetate, and Stress

Sponsor: Yale University

View on ClinicalTrials.gov

Summary

The purpose of this study is to learn how drinking alcohol affects how people experience stress and how that is affected by the body's chemistry. Specifically, the investigators will be studying relationships of drinking and a stress hormone called cortisol. The investigators believe that results will lead us to find more effective ways to help people stop or reduce drinking when participants are drinking at harmful levels.

Official title: Role of Acetate in Heavy Drinking

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2024-11-06

Completion Date

2030-01

Last Updated

2025-07-28

Healthy Volunteers

Yes

Interventions

OTHER

Deuterium Metabolic Imaging with deuterated acetate tracer

Deuterium Metabolic Imaging (DMI) is a method by which Magnetic Resonance Spectroscopy (MRS) is used to map the appearance of deuterium from a tracer source (e.g., deuterated acetate) in products of metabolism. In this case we will map the combination of glutamate and glutamine, called Glx, to serve as a tag to measure the brain's rate of acetate consumption. That is, the more deuterium appears in Glx, the more acetate that part of the brain consumes.

Locations (2)

The Anlyan Center, 300 Cedar St.

New Haven, Connecticut, United States

Yale University

New Haven, Connecticut, United States