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RECRUITING
NCT06584773
PHASE4

Efficacy of a Quadruple Immunosuppressor Regimen With mTOR Inhibitors in Sensitized Kidney Transplant Patients

Sponsor: University of Sao Paulo General Hospital

View on ClinicalTrials.gov

Summary

In this study, sensitized renal transplant recipients, who present an increased risk of acute rejection, will be evaluated for the benefit of quadruple immunosuppression, adding sirolimus to the traditional scheme with tacrolimus, mycophenolate, and prednisone.

Official title: Efficacy and Impact on CMV Infection of a Quadruple Immunosuppressor Regimen With mTOR Inhibitors in Sensitized Kidney Transplant Patients

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2015-06

Completion Date

2025-07

Last Updated

2024-09-05

Healthy Volunteers

No

Interventions

DRUG

Everolimus

mTORi added as the fourth maintenance immunosuppressive drug in recipients

DRUG

standard maintenance immunosuppression

standard maintenance immunosuppression: tacrolimus, mycophenolate, prednisone

Locations (1)

Renal Transplantation Service

São Paulo, Brazil