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Efficacy of a Quadruple Immunosuppressor Regimen With mTOR Inhibitors in Sensitized Kidney Transplant Patients
Sponsor: University of Sao Paulo General Hospital
Summary
In this study, sensitized renal transplant recipients, who present an increased risk of acute rejection, will be evaluated for the benefit of quadruple immunosuppression, adding sirolimus to the traditional scheme with tacrolimus, mycophenolate, and prednisone.
Official title: Efficacy and Impact on CMV Infection of a Quadruple Immunosuppressor Regimen With mTOR Inhibitors in Sensitized Kidney Transplant Patients
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2015-06
Completion Date
2025-07
Last Updated
2024-09-05
Healthy Volunteers
No
Interventions
Everolimus
mTORi added as the fourth maintenance immunosuppressive drug in recipients
standard maintenance immunosuppression
standard maintenance immunosuppression: tacrolimus, mycophenolate, prednisone
Locations (1)
Renal Transplantation Service
São Paulo, Brazil