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tVNS in Long COVID-19
Sponsor: Icahn School of Medicine at Mount Sinai
Summary
A prior open label study has shown that transcutaneous vagus nerve stimulation \[tVNS\] can improve the health of some patients with postacute sequelae of SARS-CoV-2 infection (PASC), severely affected enough to also fulfill criteria for myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS). The purpose of this study is to compare two sets of stimulus parameters to determine the one that best improves the health-related quality of life of these patients over a period of 6-weeks. Patients using their assigned device for at least 30 of the 42 possible opportunities will receive the best device for an additional 6-week period.
Official title: Use of Transcutaneous Vagus Nerve Stimulation in Reducing the Symptoms of Long COVID Patients Who Fulfill Diagnostic Criteria for ME/CFS
Key Details
Gender
All
Age Range
21 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2024-11-01
Completion Date
2026-12-31
Last Updated
2025-08-08
Healthy Volunteers
No
Conditions
Interventions
Transcutaneous vagus nerve stimulator
A device attached to the tragus of the ear which when activated stimulates an ascending branch of the vagus nerve
Locations (1)
Icahn School of Medicine at Mount Sinai
New York, New York, United States