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Effect of Sodium Glucose Co-tansporter 2 Inhibitors (SGLT2I) on Inflammatory and Oxidative Stress Markers Level in Heart Failure Patients
Sponsor: Kafrelsheikh University
Summary
The aim of this study is to explore the effect of SGLT2i on the levels of cardiac biomarkers, inflammatory and stress markers in Egyptian heart failure patients to provide a better understanding of mechanism that might assist in tailoring treatment strategies in patients with various forms of HF especially in Egyptian population. Also understand how biomarkers may be employed to predict risk in patients receiving SGLT2i or identification of those who may derive the most benefit from SGLT2i in the means of individualized medicine.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2024-02-15
Completion Date
2025-06-30
Last Updated
2024-09-05
Healthy Volunteers
No
Conditions
Interventions
SGLT2 inhibitor
patients with HF are subjected to regular dose of SGLT2I member according to patient status.
echo cardiogram
the patients are subjected to ECHO to determine their EF prior to and post the study
Locations (1)
Kafrelsheikh University Hospital
Kafr ash Shaykh, Egypt