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RECRUITING
NCT06586047
EARLY_PHASE1

Breast Cancer PSMA PET

Sponsor: Ahmad Shariftabrizi

View on ClinicalTrials.gov

Summary

The purpose of this research is to determine the expression of Prostate Specific Membrane Antigen(PSMA) in metastatic Triple Negative Breast Cancer (TNBC) patients using Fludeoxyglucose F18 (FDG) PET/CT as the gold standard. The investigators hypothesize that most lesions in metastatic TNBC are PSMA-avid; and thus PSMA-based radionuclide therapy can be a valid treatment option for TNBC, and clinical trials can be designed for this purpose. Thirty metastatic TNBC patients will be enrolled and will be on the study for maximum of 4 weeks.

Official title: Evaluation of PSMA Expression in Triple Negative Breast Cancer Patients Using 18 F-DCFPyL-PET/CT

Key Details

Gender

FEMALE

Age Range

18 Years - 90 Years

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2024-08-29

Completion Date

2026-12-29

Last Updated

2026-03-27

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

PET imaging

Imaging with FDG PET/CT and Pyl PET/CT in triple negative breast cancer

Locations (1)

University of Iowa Healthcare

Iowa City, Iowa, United States