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ENROLLING BY INVITATION
NCT06586320
NA

Quantification of Parkinson's Disease Patients As a Biomarker for Classification, Prediction and Response to Treatment

Sponsor: Stardots AB

View on ClinicalTrials.gov

Summary

This is a three-armed open investigational study that aims to differentiate, quantify, and categorize abnormal eye movements and upper limbs movements in patients with Parkinson's disease. The study is using investigational non-invasive devices for that reason including ANLIVA® Hand Movement and ANLIVA® Eye Movement.

Official title: Using Mathematical Quantification of Limb and Eye Movements of Parkinson's Disease Patients As a Biomarker for Classification and Prediction of Disease State and Response to Treatment

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2025-02-06

Completion Date

2027-02-01

Last Updated

2025-02-20

Healthy Volunteers

Yes

Interventions

DRUG

150% of their routine home dopaminergic medications dose right in the clinic

IPD subjects will be informed head of time not to take their dopaminergic medications and other Parkinson's non-dopaminergic medications such as anticholinergics, NMDA inhibitors, and adenosine blockers for at least 12 hours prior to their initial procedure. Immediately, after conducting both hand movement and eye movement tests, the patient will take 150% of their routine home dopaminergic medications dose right in the clinic. They will also take their non-dopaminergic medications doses similar to home dose with no change. This will be under the supervision of their treating movement disorders specialist and study PI.

DEVICE

Evaluation of mathematical models

Evaluation of performance of mathematical models developed to quantify and classify symptoms and disease state using sensor data from smart phone and eye tracking cameras

Locations (1)

Dartmouth Hitchcock medical center

Manchester, New Hampshire, United States