Clinical Research Directory

the Clinical Effect of Nd: YAG Laser Assisted Periodontal Initial Therapy in Patients With Moderate to Severe Periodontitis

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Summary

The goal of this clinical trial is to learn if Neodymium-Doped Yttrium Aluminum Garnet（Nd: YAG） Laser-assisted non-surgical periodontal treatment is effective in treating stage II/III periodontitis. It will also evaluate the safety and impact of the laser treatment. The main questions it aims to answer are: 1. Does Nd: YAG Laser treatment reduce probing depth, gingival inflammation, and clinical attachment loss more effectively than standard Scaling and root planing(SRP) therapy alone? 2. What changes in inflammatory markers and oxidative stress levels occur when patients receive laser-assisted therapy? Researchers will compare Nd: YAG Laser treatment to standard periodontal therapy alone to determine the effectiveness of the laser treatment. Participants will: 1. Receive Nd: YAG Laser assisted therapy on one side of their mouth and standard therapy on the other side. 2. Visit the clinic at baseline, 6 weeks, and 3 months for follow-up assessments and tests. 3. Provide samples and have measurements taken of periodontal health and biomarkers of inflammation and oxidative stress.

Official title: the Clinical Effect of Nd: YAG Laser Assisted Periodontal Initial Therapy in Patients With Moderate to Severe Periodontitis: a Split-mouth, Randomized, Controlled Clinical Trial

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