Clinical Research Directory

Inclusion Criteria: * Male or female patients aged 18 years and older who have a unilateral impacted mandibular third molar that is indicated for extraction with bone removal and the presence of an adjacent second molar. Exclusion Criteria: * Soft tissue impaction that will not need any bone removal. * Presence of any acute oral infection including active Pericoronitis. * Patients who have undergone radiotherapy in the head and neck region, chemotherapy or systemic long-term corticosteroid treatment. * Patients receiving medications known to induce gingival hyperplasia; anticonvulsant (phenytoin), immunosuppressant (cyclosporine A), and various calcium channel blockers (nifedipine, verapamil, diltiazem). * Patients who have taken systemic antibiotics less than 3 months prior to baseline. * Presence of uncontrolled diabetes, severe nutritional deficiencies and endocrine disturbances. * Presence of immune deficiency or any immune disease. * Intravenous bisphosphonates or Oral bisphosphonate intake for more than 3 years. * Smokers and alcoholics. * Pregnant or lactating females. * Hypersensitivity to one of the ingredients listed in any of the mouthwashes, especially chlorhexidine as reactions to this has been reported in the literature.