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RECRUITING
NCT06589089
PHASE2

Autologous Hematopoietic Stem Cell Boost Study After CAR-T Therapy

Sponsor: Ruijin Hospital

View on ClinicalTrials.gov

Summary

This is a prospective, single-arm, open study to observe the efficacy and safety of the CART-SCB regimen (Clinical Regimen for the Prospective Study of Autologous Hematopoietic Stem Cell Boost for the Improvement of Bone Marrow Suppression in Patients with High-Risk Immunohematologic Toxicity Lymphoma After Chimeric Antigen Receptor T (CAR-T)-Cell Immunotherapy Therapy) . After the patient has completed CAR-T therapy, if the patient has unrelieved hematologic toxicity, consider infusing a reserve of stem cells; if myelosuppression has not been significantly relieved, stem cell infusion can be performed again.

Official title: Prospective Study of Autologous Hematopoietic Stem Cell Boost to Improve Myelosuppression in B-NHL Patients with High-risk Immunologic Hematologic Toxic After Chimeric Antigen Receptor T-Cell Immunotherapy

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

18

Start Date

2024-10-15

Completion Date

2025-12

Last Updated

2024-10-23

Healthy Volunteers

No

Interventions

DRUG

autologous hematopoietic stem cell

Intervention were given myelosuppression occurring that cannot be controlled with other drugs as judged by the investigators

Locations (1)

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, China