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Does Oral Lactate Affect Gut Hormone Secretion in a Dose-response Relationship?
Sponsor: University of Aarhus
Summary
To investigate whether there is a linear dose-response relationship between oral lactate and its effects on gut hormone secretion, motility, and appetite. Hypothesis Oral lactate administration affects gut hormone secretion, insulin levels, motility, appetite sensation and the amount of food intake in a linear dose-response relationship.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2024-10
Completion Date
2025-01
Last Updated
2024-09-19
Healthy Volunteers
Yes
Conditions
Interventions
Placebo
Placebo (300 mL salt water, NaCl) = CTR
LAC5
5 g lactate (300 mL lactate drink = 5 g D/L-lactate bound to Na) = LAC5
LAC10
10 g lactate (300 mL lactate drink = 10 g D/L-lactate bound to Na) = LAC10
LAC20
20 g lactate (300 mL lactate drink = 20 g D/L-lactate bound to Na) = LAC20
Locations (1)
Steno Diabetes Center Aarhus, Aarhus University Hospital
Aarhus, Aarhus N, Denmark