Clinical Research Directory

REVerse Intestinal Metaplasia in the Stomach (REVISE)

Sponsor: Katherine Garman

Summary

This study is designed to test the use of Pyrvinium vs placebo as a treatment for gastric intestinal metaplasia with features associated with increased risk of cancer. Response will be determined by assessing the extent and quality of the gastric intestinal metaplasia before and after treatment. A secondary aim will be to generate gastric organoids from patient-derived samples to test the effects of pyrvinium in vitro in patient-derived samples, and also to identify new drugs that may help reverse gastric intestinal metaplasia.

Official title: Therapeutic Intervention to Reverse Gastric Precancer

Key Details

Conditions

Interventions

Locations (1)