Clinical Research Directory

a Foundational Model for Cardiovascular Disease Diagnosis and Prediction

Sponsor: Shanghai Zhongshan Hospital

Summary

The goal of this observational study is to develop and evaluate the efficacy of a foundational model that integrates multimodal medical data to improve the diagnosis and prediction of cardiovascular diseases in patients aged 18 and older, including those with various heart conditions such as coronary artery disease, heart failure, and arrhythmias. The main questions it aims to answer are: Can a multimodal data-based diagnostic model match or exceed the accuracy of traditional gold-standard methods like coronary angiography, MRI, and echocardiography? Does integrating different types of data (ECG, imaging, biochemical tests) improve diagnostic accuracy and prediction of cardiovascular disease outcomes? Researchers will compare the foundational model with traditional diagnostic methods to see if the model offers better sensitivity, specificity, and prediction accuracy across different heart disease types. Participants will: Provide data from past medical records, including ECG, echocardiography, cardiac MRI, and biochemical tests. Undergo further data collection if necessary, in line with standard clinical procedures for cardiovascular disease management.

Official title: Development and Clinical Application of a Foundational Model for Cardiovascular Disease Diagnosis and Prediction Based on Multimodal Medical Big Data

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