Clinical Research Directory

Inclusion Criteria: * Age ≥18 years of age * Acute decompensated HF as a primary cause of hospitalization. Hospitalizations for acute decompensated HF will be determined by local clinician-investigators but should include findings of acute HF (i.e., symptoms, signs, and/or laboratory/imaging abnormalities) and treatments aimed at acute HF (e.g., intravenous diuretics, vasodilators, or inotropes). Participants with a new diagnosis of HF may be enrolled. The enrollment will be monitored to ensure no more than 2/3 of the total cohort has new-onset HF. * Fluent in written and spoken English Exclusion Criteria: * Optimized or nearly optimized on evidence-based medical therapies for HF as determined by local investigator * Current pregnancy * Chronic use of intravenous inotropic medications including milrinone, dobutamine, or dopamine * eGFR of \<20 mL/min/1.73m2 ongoing chronic dialysis at screening. The eGFR should be estimated using the 2021 Chronic Kidney Disease Epidemiology Collaboration (2021 CKD-EPI) creatinine equation. * History of prior heart transplant or currently listed for heart transplant * Current left ventricular assist device or planned left ventricular assist device in the next 6 months * Currently receiving hospice care * Chronically resides in an assisted living or skilled nursing facility where medications are managed by facility personnel * Terminal illness other than HF with a life expectancy of \<1 year as determined by the enrolling clinician-investigator