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Fecal Microbiota Transplant for Anorexia Nervosa
Sponsor: McMaster University
Summary
The purpose of this pilot randomized-controlled trial is to determine whether Fecal Microbiota Transplant (FMT) treatment demonstrates feasibility, acceptability, and prelinary effectiveness among patients with anorexia nervosa (AN). Specifically, the investigators aim to compare changes in weight, gut microbiome, urine, blood biomarkers and mood symptoms between participants receiving the FMT intervention and placebo.
Official title: A Pilot Feasibility Randomized Controlled Trial of Fecal Microbiota Transplant for Adolescent Anorexia Nervosa
Key Details
Gender
FEMALE
Age Range
12 Years - 17 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2025-01-01
Completion Date
2026-06
Last Updated
2024-11-22
Healthy Volunteers
No
Conditions
Interventions
Fecal Microbiota Transplant
An investigational biologic comprised of 15.0g of dried healthy donor stool contained within a size 00 gelatin capsule, to be taken twice per day, twice per week over an 8-week duration.
Placebo
Oral placebo capsules (OPC) containing methylcellulose, to be taken twice per day, twice per week over an 8-week duration.