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RECRUITING
NCT06595459
PHASE4

The Options 2 Study

Sponsor: University of Wisconsin, Madison

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to investigate how well nicotine pouches and nicotine mini lozenges serve as substitutes for cigarettes when people try to switch from smoking to using these alternate nicotine products. Participants will: * Use nicotine pouches, nicotine mini lozenges, or no study product for a week and then try not to smoke for 3 weeks. * Have 6 in-person research visits and 1 follow-up call * Complete questionnaires at each study contact and use a smartphone app to record smoking and study product use

Official title: A Randomized Comparative Effectiveness Trial of Nicotine Pouches for Cigarette Substitution: A Question of Public Health

Key Details

Gender

All

Age Range

21 Years - Any

Study Type

INTERVENTIONAL

Enrollment

300

Start Date

2025-05-21

Completion Date

2029-07-30

Last Updated

2025-09-04

Healthy Volunteers

No

Interventions

DRUG

Nicotine Pouches

3mg or 6mg nicotine pouches

DRUG

Mini Nicotine lozenges

2mg to 4mg mini lozenges

Locations (1)

University of Wisconsin

Madison, Wisconsin, United States