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The Options 2 Study
Sponsor: University of Wisconsin, Madison
Summary
The goal of this clinical trial is to investigate how well nicotine pouches and nicotine mini lozenges serve as substitutes for cigarettes when people try to switch from smoking to using these alternate nicotine products. Participants will: * Use nicotine pouches, nicotine mini lozenges, or no study product for a week and then try not to smoke for 3 weeks. * Have 6 in-person research visits and 1 follow-up call * Complete questionnaires at each study contact and use a smartphone app to record smoking and study product use
Official title: A Randomized Comparative Effectiveness Trial of Nicotine Pouches for Cigarette Substitution: A Question of Public Health
Key Details
Gender
All
Age Range
21 Years - Any
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2025-05-21
Completion Date
2029-07-30
Last Updated
2025-09-04
Healthy Volunteers
No
Conditions
Interventions
Nicotine Pouches
3mg or 6mg nicotine pouches
Mini Nicotine lozenges
2mg to 4mg mini lozenges
Locations (1)
University of Wisconsin
Madison, Wisconsin, United States