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Multi-Strain Probiotics Supplementation With Standard Care in Mild to Moderate Ulcerative Colitis
Sponsor: National University of Malaysia
Summary
Probiotics are one of the adjunctive treatments that have been extensively explored for Ulcerative colitis (UC) disease management. Probiotics, a group of beneficial bacteria, can bring various health benefits when adequately supplied to the body, especially for gut wellness. In particular, for UC patients, gut dysbiosis is one of the contributing factors in their pathogenesis. Thus, the supplementation of probiotics in combination with standard treatment can potentially help in relieving symptoms as well as promoting mucosal healing for long-term remission.
Official title: Assessing Gut Microbiota, Mucosal Healing Markers, and Metabolites in Mild to Moderate Ulcerative Colitis Treated With Multi-Strain Probiotics
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
124
Start Date
2024-02-23
Completion Date
2026-02
Last Updated
2025-03-12
Healthy Volunteers
No
Conditions
Interventions
Multi-Strain Probiotics
Each sachet of the multi-strain probiotics contain 30 billion CFU of 6 strains which includes Lactobacillus acidophilus BCMC®12130, Lactobacillus casei subsp BCMC®12313, Lactobacillus lactis BCMC®12451, Bifidobacterium bifidum BCMC®02290, Bifidobacterium infantis BCMC®02129, Bifidobacterium longum BCMC®02120
Placebo
Replicate for multi-strain probiotics without any active ingredients
Locations (1)
Hospital Canselor Tuanku Muhriz UKM
Cheras, Kuala Lumpur, Malaysia