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Developing a Combined Molecular Screening and Triage Test for Cervical Cancer in Self-samples
Sponsor: Universiteit Antwerpen
Summary
The goal of the COMBISCREEN project is to develop a fully molecular cervical screening and triage approach that is applicable on self-samples, which are an easily accessible and non-invasive source of biomarkers. The project allows a one-step screening and triage modality and thereby identifies women with clinically relevant disease that are in need of treatment.
Official title: Developing a Combined Molecular Screening and Triage Test for Cervical Cancer Based on Human Papillomavirus (HPV) Detection, Quantification, Genotyping and DNA Methylation in Self-samples (COMBISCREEN)
Key Details
Gender
FEMALE
Age Range
25 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2024-03-28
Completion Date
2037-02-28
Last Updated
2024-09-19
Healthy Volunteers
No
Conditions
Interventions
Colli-Pee 20mL device with UCM
Women will collect a first-void urine (the initial part of the urine stream) sample at home the day before a hospital appointment using the 20mL Colli-Pee device prefilled with urine conservation medium (UCM, Novosanis, Belgium).
Evalyn Brush
Women will collect a vaginal self-sample using the Evalyn Brush (Rovers Medical Devices, The Netherlands) at home the day before a hospital appointment.
Locations (1)
Universitair Ziekenhuis Antwerpen (UZA)
Edegem, Antwerpen, Belgium