Clinical Research Directory

Inclusion Criteria: * Post-menopausal female between age 55 and 89 * No post-menopausal bleeding * Diagnosis of recurrent urinary tract infection (UTI) in the electronic health record or as two culture proven UTIs in 6 months or three culture proven UTIs in 12 months * At least one UTI in the 6 months prior to entering the study * Asymptomatic for UTI symptoms at the time of enrollment. * On vaginal estrogen therapy for at least 6 weeks prior to enrollment * Ready access to email and internet Exclusion Criteria: * Recent prophylactic antibiotic use (washout period of 4 weeks) * Neurogenic bladder * Diagnosis of urinary retention * Uncorrected Stage III-IV prolapse * Indwelling catheter or need for intermittent self-catheterization * History of complicated UTIs * History of interstitial cystitis or bladder pain syndrome * History of fecal incontinence/accidental bowel leakage * Greater than 14 bowel movements per week * Non-English speaking * Allergy to chlorhexidine gluconate * Inability to utilize vaginal estrogen therapy * Recent urogynecological or urologic surgery (\<12 weeks)