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Innovative Drug Delivery Nanophotonic Platform for Implementation of Sarcoma Therapy
Sponsor: Istituto Ortopedico Rizzoli
Summary
DEEPLY aims to improve sarcoma therapy by the development of an innovative nanophotonic delivery approach to be applied in the future as an integrated local therapy for patients with inoperable tumors or with oligometastases. The major aim of the project is the development of innovative nanocarriers loaded with chemotherapeutic agents, whose delivery will be improved by the use of an optic fiber (optoporation). After the synthesis, and characterization of NPs, a prototype will be produced and preclinically validated on patient-derived biological material. This wide comprehensive methodological approach will ensure the obtainment of robust data to be faster exploited toward clinical applications.
Key Details
Gender
All
Age Range
2 Years - 85 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2024-08-30
Completion Date
2026-08-30
Last Updated
2025-09-22
Healthy Volunteers
No
Conditions
Locations (2)
Istituto Ortopedico Rizzoli-OSOTT
Bologna, Emilia-Romagna, Italy
IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori
Meldola, Emilia-Romagna, Italy