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NOT YET RECRUITING
NCT06600711
PHASE3

Nitazoxanide for Treatment of Cryptosporidium in Children

Sponsor: Johns Hopkins Bloomberg School of Public Health

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if nitazoxanide (NTZ) can treat Cryptosporidium infection in children age 6-12 months. The main questions it aims to answer are: * Does NTZ treatment of diarrheal Cryptosporidium infection lower the number of days of diarrhea? * Does NTZ treatment of diarrheal and non-diarrheal Cryptosporidium infection lower the number of days that parasites can be found in the stool? Researchers will compare NTZ to a placebo (a look-alike substance that contains no drug) to see if NTZ works to treat Cryptosporidium. Participants will: * Take NTZ or placebo for 3 days * Receive regular visits from field research assistants * Provide blood and urine samples

Official title: Randomized Control Trial of Nitazoxanide for the Treatment of Cryptosporidium Infection in Malnourished Children in Bangladesh

Key Details

Gender

All

Age Range

6 Months - 12 Months

Study Type

INTERVENTIONAL

Enrollment

480

Start Date

2026-04-01

Completion Date

2030-05

Last Updated

2026-02-12

Healthy Volunteers

No

Interventions

DRUG

Nitazoxanide

5 mL suspension (100 mg), 2x/day for 3 days

DRUG

Placebo

identical in consistency, appearance, and taste to nitazoxanide suspension. 5 mL suspension given 2x/day for 3 days