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Efficacy of Locally Delivered Rosemary Extract Gel in Management of Periodontitis
Sponsor: Ain Shams University
Summary
Rosemary extract is known for its antibacterial, anti-inflammatory and anti-oxidant properties that make it a promising therapeutic aid as a local delivery drug in deep periodontal pockets in adjunct to non-surgical periodontal therapy in management of periodontitis. These properties are due to the high content of phenolic compounds such as carnosic acid, urolic acid, rosmarinic acid or chlorogenic acid. Rosemary extract was previously investigated and proved its effectiveness against periodontopathogens in-vitro. Thus, its selected for this study to be administered in a gel form to assess its efficacy in management of periodontitis.
Official title: Efficacy of Locally Delivered Rosemary Extract Gel As an Adjunct to Non-Surgical Periodontal Therapy in Management of Periodontitis (A Randomized Controlled Clinical Trial with Microbiological Analysis)
Key Details
Gender
All
Age Range
25 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
16
Start Date
2024-10
Completion Date
2025-06
Last Updated
2024-09-19
Healthy Volunteers
No
Interventions
Herbal therapy
rosemary extract gel is used for the first time as a local drug delivery as an adjunct to non-surgical periodontal therapy in management of stage III periodontitis patients.
Placebo Drug
a placebo gel will be applied in deep pockets (\>5mm) in stage III periodontitis patients as an adjunct to non-surgical periodontal therapy
Locations (1)
Faculty of Dentistry - Ain Shams University
Cairo, Egypt