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Surgiphor Us in TSA
Sponsor: Rothman Institute Orthopaedics
Summary
Bacteria is occasionally present in the shoulder during shoulder arthroplasty surgery and is hypothesized to increase the risk of failure of the prosthesis. Surgiphor (sterile Povidone-Iodine) wound irrigation, is a solution used in orthopaedic surgery and other surgical fields to kill bacteria intraoperatively. The Iodine dissociates from complex and has antimicrobial properties, causing cell death of bacteria, fungi, and viruses through interactions with proteins, nucleotides, and fatty acids in the cytoplasm and cytoplasmic membrane. This study examines the use of Povidone-Iodine during primary shoulder arthroplasty.
Official title: Effect of Surgiphor (sterile Povidone-Iodine) Wound Irrigation on Rate of Positive Deep Culture and NGS in Primary Total Shoulder Arthroplasty- a Prospective, Randomized Pilot Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
126
Start Date
2024-09-16
Completion Date
2025-09-30
Last Updated
2024-09-19
Healthy Volunteers
Yes
Interventions
sterile saline solution
The shoulder will be washed with normal sterile saline before and after placing the shoulder implant
Surgiphor
The shoulder will be washed with Surgiphor (Povidone Iodine) before and after placing the shoulder implant
Sample Collection
During the surgical procedure, 4 swabs of the surgical wound will be taken at various times throughout the procedure
Locations (1)
Rothman Orthopaedic Institute
Philadelphia, Pennsylvania, United States