Clinical Research Directory

Inclusion Criteria: * Adults with confirmed diagnosis of UC - Group 1 criterion: ≥18 years of age regardless of gender * Group 2 criterion: ≥30 years of age for males and ≥40 years of age for females * Active disease confirmed by endoscopy (endoscopic Mayo score ≥ 2) * Indication to start treatment with filgotinib AND one of the following criteria: * Active disease confirmed by intestinal ultrasound (BWT \> 3 mm in at least one bowel segment and at least one other pathological IUS parameter) or * Increased CRP (\>5 mg/L) and/or fecal calprotectin levels (\>250 mg/kg) Exclusion Criteria: * Pregnancy * Unable to provide informed consent * Colorectal carcinoma or high-grade dysplasia