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Genomics and Microbiome Investigation in Cases of Recurrent Pregnancy Losses
Sponsor: Hospital de Clinicas de Porto Alegre
Summary
Recurrent pregnancy losses (RPL) are characterized by the occurrence of more than one spontaneous pregnancy loss. It is caused by different known factors, but about half of the cases remain without an explanation. Efforts are being done in the scientific community to solve this cases. In this study, the investigators aim to investigate genetic factors that might predispose to RPL, as well as the influence of the uterine microbiota (microorganisms that normally live in the uterus of women).
Official title: Evaluation of Predisposing Factors for Idiopathic Recurrent Pregnancy Losses: a Study Using a Genomic and Microbiota Approach
Key Details
Gender
FEMALE
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
20
Start Date
2023-04-14
Completion Date
2025-12
Last Updated
2024-09-19
Healthy Volunteers
No
Conditions
Interventions
Exome test
An exome will be performed on the participants of RPL group.
Microbiota analysis
A cervical microbiota analysis will be performed in the RPL and control groups.
Locations (1)
Hospital de Clínicas de Porto Alegre (HCPA)
Porto Alegre, Rio Grande do Sul, Brazil