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Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)
Sponsor: University of Illinois at Urbana-Champaign
Summary
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in middle-aged adults. Our research team will evaluate three different groups: the first group will be chosen using a predictive analytics model that predicts who will benefit most from the MIND diet, the second group will follow the MIND diet without being pre-selected, and the third group will eat a standard healthy diet to serve as a comparison. The main questions it aims to answer are: Does the MIND diet improve cognitive performance and heart health relative to a control diet? How does the health impact of the MIND diet in participants pre-identified through predictive analytics compare to those without such pre-selection? Which of the three groups - predictive analytics selected MIND diet group, standard MIND diet group, or healthy control - demonstrate the most significant improvements in cognitive and cardiovascular health over the course of the trial? Participants will: Consume one meal that follows the MIND diet or a control meal every day for 3 months. Visit the lab before and after the 3 months of meals for tests. Keep a record of the food they eat during the study.
Official title: Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes: Examining the Effects of the Mediterranean-DASH Intervention for Neurodegenerative Delay(MIND) on Cognitive Performance, Metabolic Health and Lifestyle Outcomes Using Advanced Machine Learning Strategies
Key Details
Gender
All
Age Range
45 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
72
Start Date
2024-07-03
Completion Date
2027-12-31
Last Updated
2024-09-20
Healthy Volunteers
Yes
Interventions
MIND Diet
Daily meals designed to increase adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) dietary pattern.
Control Diet
Daily meals designed to increase fruit, vegetable, and whole grain intake consistent with a healthy American diet.
Locations (1)
University of Illinois at Urbana-Champaign
Urbana, Illinois, United States