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RECRUITING
NCT06605898
NA

Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)

Sponsor: University of Illinois at Urbana-Champaign

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in middle-aged adults. Our research team will evaluate three different groups: the first group will be chosen using a predictive analytics model that predicts who will benefit most from the MIND diet, the second group will follow the MIND diet without being pre-selected, and the third group will eat a standard healthy diet to serve as a comparison. The main questions it aims to answer are: Does the MIND diet improve cognitive performance and heart health relative to a control diet? How does the health impact of the MIND diet in participants pre-identified through predictive analytics compare to those without such pre-selection? Which of the three groups - predictive analytics selected MIND diet group, standard MIND diet group, or healthy control - demonstrate the most significant improvements in cognitive and cardiovascular health over the course of the trial? Participants will: Consume one meal that follows the MIND diet or a control meal every day for 3 months. Visit the lab before and after the 3 months of meals for tests. Keep a record of the food they eat during the study.

Official title: Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes: Examining the Effects of the Mediterranean-DASH Intervention for Neurodegenerative Delay(MIND) on Cognitive Performance, Metabolic Health and Lifestyle Outcomes Using Advanced Machine Learning Strategies

Key Details

Gender

All

Age Range

45 Years - 64 Years

Study Type

INTERVENTIONAL

Enrollment

72

Start Date

2024-07-03

Completion Date

2027-12-31

Last Updated

2024-09-20

Healthy Volunteers

Yes

Interventions

OTHER

MIND Diet

Daily meals designed to increase adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) dietary pattern.

OTHER

Control Diet

Daily meals designed to increase fruit, vegetable, and whole grain intake consistent with a healthy American diet.

Locations (1)

University of Illinois at Urbana-Champaign

Urbana, Illinois, United States