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ACTIVE NOT RECRUITING
NCT06606106
PHASE1

A Study of LY3537031 in Overweight, Obese, and Healthy Participants

Sponsor: Eli Lilly and Company

View on ClinicalTrials.gov

Summary

This is a 4-part study that includes a Part A, Part B, Part C, and Part D. Parts A and D will study the safety and tolerability of the study drug known as LY3537031 in participants who are overweight and obese. Part B and Part C will study the safety and tolerability of LY3537031 in healthy participants. Part C will contain only Japanese and Chinese healthy participants. Blood tests will be performed to check how much LY3537031 gets into the bloodstream and how long it takes the body to eliminate it. Body weight will be measured. The study will last approximately 49 weeks excluding a screening period.

Official title: A Multiple-Ascending Dose Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of LY3537031 in Overweight and Obese Participants and Healthy Volunteers

Key Details

Gender

All

Age Range

22 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

302

Start Date

2024-09-05

Completion Date

2026-07

Last Updated

2026-01-20

Healthy Volunteers

Yes

Interventions

DRUG

LY3537031

Administered SC

DRUG

Placebo

Administered SC

Locations (5)

Collaborative Neuroscience Research, LLC

Los Alamitos, California, United States

Fortrea Clinical Research Unit

Daytona Beach, Florida, United States

Clinical Pharmacology of Miami

Miami, Florida, United States

QPS

Springfield, Missouri, United States

Fortrea Clinical Research Unit

Dallas, Texas, United States