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A Study of LY3537031 in Overweight, Obese, and Healthy Participants
Sponsor: Eli Lilly and Company
Summary
This is a 4-part study that includes a Part A, Part B, Part C, and Part D. Parts A and D will study the safety and tolerability of the study drug known as LY3537031 in participants who are overweight and obese. Part B and Part C will study the safety and tolerability of LY3537031 in healthy participants. Part C will contain only Japanese and Chinese healthy participants. Blood tests will be performed to check how much LY3537031 gets into the bloodstream and how long it takes the body to eliminate it. Body weight will be measured. The study will last approximately 49 weeks excluding a screening period.
Official title: A Multiple-Ascending Dose Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of LY3537031 in Overweight and Obese Participants and Healthy Volunteers
Key Details
Gender
All
Age Range
22 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
302
Start Date
2024-09-05
Completion Date
2026-07
Last Updated
2026-01-20
Healthy Volunteers
Yes
Conditions
Interventions
LY3537031
Administered SC
Placebo
Administered SC
Locations (5)
Collaborative Neuroscience Research, LLC
Los Alamitos, California, United States
Fortrea Clinical Research Unit
Daytona Beach, Florida, United States
Clinical Pharmacology of Miami
Miami, Florida, United States
QPS
Springfield, Missouri, United States
Fortrea Clinical Research Unit
Dallas, Texas, United States