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RECRUITING
NCT06606769
NA

Physical Activity Guarantees Bone Density.

Sponsor: Poznan University of Physical Education

View on ClinicalTrials.gov

Summary

Bone tissue is crucial for overall health and quality of life, but it undergoes constant internal remodeling, leading to osteoporosis, a widespread bone disease. Regular physical activity can improve bone mineral density (BMD) and prevent osteoporosis. Studies have shown that premenopausal women with regular physical activity have greater BMD. Diagnosing bone resorption is essential, and dual-energy X-ray absorptiometry tests (DXA) and circulating microRNAs (miRNAs) may offer more prognostic potential than conventional markers. The gut microbiome may also regulate bone metabolism, with metabolites like trimethylamine N-oxide (TMAO) playing a role. A project aims to promote systematic physical activity to improve BMD and well-being, support societal mobilization, and conduct preventive examinations for osteoporosis risk. Implementing systematic prevention is important not only for health but also for reducing social and financial costs associated with osteoporosis and associated fractures.

Official title: Fizyczne Aktywnosci Gwarantem Zdrowych Kosci

Key Details

Gender

FEMALE

Age Range

50 Years - Any

Study Type

INTERVENTIONAL

Enrollment

300

Start Date

2024-09-13

Completion Date

2027-06-30

Last Updated

2024-10-10

Healthy Volunteers

Yes

Interventions

OTHER

Exercise

supervised exercise training; twice a week for 12 months

Locations (1)

Poznan University of Physical Education

Poznan, Poland