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Physical Activity Guarantees Bone Density.
Sponsor: Poznan University of Physical Education
Summary
Bone tissue is crucial for overall health and quality of life, but it undergoes constant internal remodeling, leading to osteoporosis, a widespread bone disease. Regular physical activity can improve bone mineral density (BMD) and prevent osteoporosis. Studies have shown that premenopausal women with regular physical activity have greater BMD. Diagnosing bone resorption is essential, and dual-energy X-ray absorptiometry tests (DXA) and circulating microRNAs (miRNAs) may offer more prognostic potential than conventional markers. The gut microbiome may also regulate bone metabolism, with metabolites like trimethylamine N-oxide (TMAO) playing a role. A project aims to promote systematic physical activity to improve BMD and well-being, support societal mobilization, and conduct preventive examinations for osteoporosis risk. Implementing systematic prevention is important not only for health but also for reducing social and financial costs associated with osteoporosis and associated fractures.
Official title: Fizyczne Aktywnosci Gwarantem Zdrowych Kosci
Key Details
Gender
FEMALE
Age Range
50 Years - Any
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2024-09-13
Completion Date
2027-06-30
Last Updated
2024-10-10
Healthy Volunteers
Yes
Conditions
Interventions
Exercise
supervised exercise training; twice a week for 12 months
Locations (1)
Poznan University of Physical Education
Poznan, Poland