Clinical Research Directory

Inclusion Criteria： 1. Be older than 45 years old; 2. Patients admitted to the Department of Neurology due to headache, vertigo, anxiety, etc.; 3. There were no symptoms of neurological deficit on physical examination; 4. Able to cooperate with the improvement of brain MRI examination; 5. Sign the informed consent form. Exclusion Criteria: 1. History of stroke, traumatic brain injury, intracranial tumor, central nervous system infection, active malignant tumor, thyroid disease, autoimmune disease, active or chronic inflammatory disease, severe liver and kidney impairment, etc.; 2. accompanied by neurological deficit symptoms; 3. refusal to participate in the study; 4. Other conditions judged by the investigator to be unsuitable for enrollment.