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Platelet Rich Plasma in the Prevention of Adhesion Reformation
Sponsor: Fu Xing Hospital, Capital Medical University
Summary
Asherman syndrome, which occurs after trauma to the basalis layer of the endometrium. It seems that the role of postoperative platelet rich plasma（PRP）therapy in the prevention of recurrence of IUA is still controversial. To investigate if PRP therapy can prevent adhesion reformation after adhesiolysis. After the completion of hysteroscopic adhesiolysis, recruited patients will be randomized to one of the two treatment groups by computer-generated numbers: having PRP after hysteroscopic adhesiolysis; and the control group without PRP treatment. A second-look hysteroscopy and ultrasound assessment of the endometrium will be carried out 4 weeks after the surgery, and again at 8 weeks after the surgery.
Official title: The Effect of Platelet Rich Plasma in the Prevention of Adhesion Reformation After Hysteroscopic Adhesiolysis
Key Details
Gender
FEMALE
Age Range
20 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
46
Start Date
2023-10-10
Completion Date
2025-06-01
Last Updated
2025-03-11
Healthy Volunteers
No
Conditions
Interventions
PRP group
After the completion of hysteroscopic adhesiolysis, recruited participants will be randomized to one of the two treatment groups by computer-generated numbers: Immediately administer uterine perfusion with PRP after surgery, and administered PRP perfusion during hysteroscopy at 4 and 8 weeks after hysteroscopic adhesiolysis, A second-look hysteroscopy and ultrasound assessment of the endometrium will be carried out 4 weeks after the surgery, and again at 8 weeks after the surgery. Control group without PRP treatment.
Locations (2)
Fu Xing Hospital, Capital Medical University
Beijing, Beijing Municipality, China
Fuxing hospital
Beijing, Beijing Municipality, China