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NOT YET RECRUITING
NCT06610071
PHASE1

NIFR Image-guided Surgery for Malignant Soft Tissue Tumor With Low-dose SWIG Technique

Sponsor: The Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

View on ClinicalTrials.gov

Summary

This research study will evaluate how near-infrared fluorescence (NIRF) imaging with low-dose second window indocyanine green (ICG) can assist in the radical resection and pathologic diagnosis of malignant soft tissue sarcoma, such as dermatofibrosarcoma protuberans (DFSP) and skin squamous cell carcinoma (sSCC) during surgery.

Official title: Near-infrared Fluorescence Image-guided Surgery for Malignant Soft Tissue Tumor With Low-dose Second Window Indocyanine Green Technique: a Multicenter Randomized Controlled Trial

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

592

Start Date

2024-10-30

Completion Date

2030-12-30

Last Updated

2024-09-24

Healthy Volunteers

No

Interventions

DRUG

ICG administration

The ICG was injected intravenously 24 hours before surgery at a dose of 0.25 mg/kg in the first experimental group.

DRUG

ICG administration

The ICG was injected intravenously 24 hours before surgery at a dose of 25 mg/patient in the second experimental group.

DRUG

ICG administration

The ICG was injected intravenously 24 hours before surgery at a dose of 0.25 mg/kg in the first experimental group

DRUG

ICG administration

The ICG was injected intravenously 24 hours before surgery at a dose of 25 mg/patient in the second experimental group.