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RECRUITING
NCT06611618
NA

Analysis of the Loss of Muscle Force, Power and Motor Control to Predict the Risk of Falls in Patients With Knee OA

Sponsor: Istituto Ortopedico Rizzoli

View on ClinicalTrials.gov

Summary

The twofold goal of this study is to understand the link between muscle power, muscle strength, and muscle control degradation with the risk of falling, and to develop a framework for the comprehensive and quantitative assessment of muscle power (and strength) in an elderly population of patients with knee osteoarthritis, who are at higher risk of falling. The main question it aims to answer is: ● Are muscle power and motor control degradation better predictors of falls than muscle strength in the aging population? Participants will undergo: * Muscle force assessment on a dynamometer * Muscle power assessment on a dynamometer and on isntrumented stairs * Home-based mobility monitoring * Full lower limb MRI acquisition * Gait assessment

Official title: Analisi Della Perdita di Forza e Potenza Muscolare e Del Degrado Del Controllo Motorio Per la Predizione Delle Cadute in Una Popolazione Affetta da Artrosi di Ginocchio

Key Details

Gender

All

Age Range

65 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2025-01-30

Completion Date

2026-12-12

Last Updated

2026-02-27

Healthy Volunteers

No

Interventions

OTHER

Muscle power assessment

Isokinetic dynamometry test Stair ascent/descent on instrumented stairs

OTHER

Muscle force assessment

Isometric dynamometry (Maximal Voluntary Isometric Contraction)

OTHER

Home-based mobility monitoring

Mobility monitoring with wearable sensors

DIAGNOSTIC_TEST

Magnetic Resonance Imaging

Full lower limb MRI

OTHER

Gait assessment

Motion capture, surface EMG and gorund reaction force data

Locations (1)

IRCCS Istituto Ortopedico Rizzoli

Bologna, Italy