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Analysis of the Loss of Muscle Force, Power and Motor Control to Predict the Risk of Falls in Patients With Knee OA
Sponsor: Istituto Ortopedico Rizzoli
Summary
The twofold goal of this study is to understand the link between muscle power, muscle strength, and muscle control degradation with the risk of falling, and to develop a framework for the comprehensive and quantitative assessment of muscle power (and strength) in an elderly population of patients with knee osteoarthritis, who are at higher risk of falling. The main question it aims to answer is: ● Are muscle power and motor control degradation better predictors of falls than muscle strength in the aging population? Participants will undergo: * Muscle force assessment on a dynamometer * Muscle power assessment on a dynamometer and on isntrumented stairs * Home-based mobility monitoring * Full lower limb MRI acquisition * Gait assessment
Official title: Analisi Della Perdita di Forza e Potenza Muscolare e Del Degrado Del Controllo Motorio Per la Predizione Delle Cadute in Una Popolazione Affetta da Artrosi di Ginocchio
Key Details
Gender
All
Age Range
65 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2025-01-30
Completion Date
2026-12-12
Last Updated
2026-02-27
Healthy Volunteers
No
Interventions
Muscle power assessment
Isokinetic dynamometry test Stair ascent/descent on instrumented stairs
Muscle force assessment
Isometric dynamometry (Maximal Voluntary Isometric Contraction)
Home-based mobility monitoring
Mobility monitoring with wearable sensors
Magnetic Resonance Imaging
Full lower limb MRI
Gait assessment
Motion capture, surface EMG and gorund reaction force data
Locations (1)
IRCCS Istituto Ortopedico Rizzoli
Bologna, Italy