Clinical Research Directory

Inclusion Criteria: * Adults ≥ 18 years of age * Patients with a diagnosis of OSA * Patients with an apnea-hypopnea index (AHI) of 5 until 30 events per hour * Patients initially treated with MAD Exclusion Criteria: * Patients under 18 years of age * Patients without a diagnosis of mild to moderate OSA * Patients undergoing other treatments for OSA * Patients previously undergone MAD treatment (this also includes over the counter boil and bite MADs) * Patients diagnosed with central sleep apnea * Patients undergoing orthodontic treatment (e.g. braces) * Pregnant patients * Patients with craniofacial anomalies or syndromes (e.g., Treacher-Collins, Down, Pierre-Robin, Marfan), * Patients undergoing cancer treatment with chemotherapy or radiation * Patients with a history of maxillofacial surgery * Patients with select dental conditions like severe periodontal disease, temporomandibular joint disease, insufficient dentition to support appliance retention in the mouth * Patients who use bone resorption inhibitors (such as bisphosphonates, calcitonin, SERMs) or the prolonged use, ≥ 6 months of corticosteroids