Clinical Research Directory

Inclusion Criteria: Inclusion criteria for healthy individuals: * Age ≥ 18 years old; * Informed consent and signed informed consent form. Inclusion criteria for patients with malignant tumors: * Patients with malignant tumors diagnosed by pathology or cytology; * Advanced stage patients who have not received modern medical treatment in the past, or early to mid-stage patients who have completed postoperative radiochemotherapy for ≥ 1 month; * Age ≥ 18 years old; * Informed consent and signed informed consent form. Exclusion Criteria: Exclusion criteria for healthy individuals: * Patients with malignant tumors diagnosed by pathology or cytology; * Those who have taken any antibiotics/probiotics within 1 month before biological sample collection; * Those with other immune or infectious diseases; * Those with severe damage to the heart, liver, lungs, or kidney functions; * Pregnant women, or those with mental illnesses such as depression or schizophrenia; * Those deemed ineligible for the study by the researcher. Exclusion criteria for patients with malignant tumors: * Patients with multiple primary cancers; * Those who have taken any antibiotics/probiotics within 1 month before biological sample collection; * Those with other immune or infectious diseases; * Those with severe damage to the heart, liver, lungs, or kidney functions; * Pregnant women, or those with mental illnesses such as depression or schizophrenia; * Those deemed ineligible for the study by the researcher.