Clinical Research Directory

Inclusion Criteria: 1. Subjects aged 45-85 years. 2. Able to provide a signed informed consent. 3. Scheduled for a screening colonoscopy at the investigation site. Exclusion Criteria: 1. Undergoing diagnostic colonoscopy for investigation of symptoms. 2. Has undergone colonoscopy within preceding nine (9) years except for a failed colonoscopy due to poor bowel preparation. Failed colonoscopy must have been within the past year and without therapeutic intervention. 3. History of colorectal cancer. 4. Family history of colorectal cancer, defined as having one or more first-degree relatives (parent, sibling, or child) with CRC at any age. 5. Subject has a diagnosis or medical / family history of any of the following conditions, including: * Familial adenomatous polyposis (also referred to as \"FAP\", including attenuated FAP and Gardner\'s syndrome), * Hereditary non-polyposis CRC syndrome (also referred to as \"HNPCC\" or \"Lynch Syndrome\"), * Other hereditary cancer syndromes including but are not limited to Peutz-Jeghers Syndrome, MYH-Associated Polyposis (MAP), Turcot\'s (or Crail\'s) Syndrome, Cowden\'s Syndrome, Juvenile Polyposis, Neurofibromatosis, or Familial Hyperplastic Polyposis. 6. Subject has a diagnosis or personal history of inflammatory bowel disease (IBD) including chronic ulcerative colitis and/or Crohn\'s disease. 7. Subjects with a disability to extend their tongue. 8. Subjects with tongue piercing. 9. Dental visit in the past 7 days prior to Gixam test. 10. Intake of pro-biotics over the past 3 months pre-Gixam test. 11. Subject has any condition that in the opinion of the Investigator should preclude participation in the study.