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Development of Tumor Organoids From Undifferentiated Primary Carcinomas to Guide Therapeutic Decisions
Sponsor: Centre Francois Baclesse
Summary
The study is based on the constitution of a collection of tumor and blood samples for the development of tumoroid for functional tests to predict clinical response to treatment.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
20
Start Date
2025-03-05
Completion Date
2032-12-15
Last Updated
2025-12-24
Healthy Volunteers
No
Conditions
Interventions
organoid etablishment
Prior to initiation of 1st-line therapy: * Collection of an additional study-specific tumor sample for tumoroid analysis (1 fresh tumor sample) * A blood test blood a for tumoroid realization and : * Analysis of ex vivo tumoroid response to treatment and correlation with patient response in vivo * Analysis of correlation between in vivo and ex vivo tumor characteristics * Analysis of first- and second-line survival rates and overall survival
Locations (1)
Centre François Baclesse
Caen, France