Inclusion Criteria:
* Consent informed, written, signed and dated
* Women or men aged 18 to 70 years inclusive
* Carrier of L. loa microfilaremia
* Body weight ≥ 40 kg and less than 90 kg
Exclusion Criteria:
* Participation in any study other than a purely observational study, within the 4 weeks preceding this study (determined by the theoretical date of the first administration of albendazole placebo)
* Any vaccination within 4 weeks previous to this study
* Infection requiring treatment in the 10 days previous to this study, as determined by the anamnesis during the medical interview (e.g. pulmonary infection , digestive or skin infection; with or without antibiotic treatment)
* Known immunosuppressive pathology (by self-report)
* Past or present history of neurological (including epilepsy) or neuropsychiatric disease
* Current treatment with ritonavir and/or rifampicin
* Use of cocaine or other drugs of abuse in the 72 hours preceding administration of the trial treatment, as determined by history during the medical interview
* Past or present history of liver, kidney or bone marrow failure
* ALAT transaminase level ≥ 3 times the upper limit of normal (3N) according to laboratory standards
* Any condition, in the opinion of the investigator, that exposes the subject to undue risk
* Known intolerance to ALB or benzimidazole derivatives in general
* Subjects who donated blood in the previous 8 weeks to study entry, with a standard volume (500 mL)
* On clinical examination: symptoms, physical signs or laboratory findings suggestive of systemic disorders, including disorders, including renal, hepatic, cardiovascular, pulmonary, skin, immunodeficiency, psychiatric and other abnormalities that could interfere with the interpretation of trial results. The physician may then give a favorable or unfavorable opinion on the participants inclusion.
* ALB and/or mebendazole in the last month
* IVM taken in the last month
* Any condition which, in the opinion of the investigator, exposes the subject to undue risk
* Positive urine pregnancy test for women of childbearing age or breastfeeding
