Clinical Research Directory
Browse clinical research sites, groups, and studies.
Screening of Coexistence Between Sickle Cell Anaemia and G6PD Deficiency
Sponsor: Fatma Hussein Mahmoud
Summary
G6PD deficiency may have a subtle effect on the severity of hemolysis and also worsen the degree of anaemia in SCD when the two disorders coexist. Therefore, selective decision should be taken in patients in whom the two conditions coexist in the choice of drug and in the treatment of infections.The prevalence of the G-6-PD deficiency is high in SCD patients, but does not differ from that observed among non-SCD subjects .However, the G-6-PD deficiency appears to worsen the clinical features of SCD, there were more hospitalizations, major vaso-occlusive crises among G-6-PD deficient sickle cell patients.
Official title: Newborn Screening of Coexistence Between Sickle Cell Anaemia and G6PD Deficiency in NEW VALLEY GOVERNORATE
Key Details
Gender
All
Age Range
1 Day - 28 Days
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2025-01
Completion Date
2026-02
Last Updated
2024-09-26
Healthy Volunteers
Yes
Conditions
Interventions
G6pd enzyme sickling test
Measuring the enzyme level of G6PD and presence of Hbs
G6PD enzyme and sickling test
Measuring enzyme level of G6PD and level of HbS
G6PD enzyme and HPLC
Measuring G6PD enzyme level in neonates and measuring level of HbS