Clinical Research Directory

Inclusion Criteria: * \- Children with a diagnosis of JIA according to the ILAR classification criteria * JIA patients who satisfy criteria for inactive disease for a minimum of 6 continuous months while still taking medication. * Patients who have been treated with cs/b/bs/ts DMARDs according to the label indication * Ability to comply with the entire study procedures, ability to communicate meaningfully with the investigational staff, competence to give written informed consent; to be applied to the parents and/or patients, as appropriate * Duly executed, written, informed consent obtained from the patient's parents/legal guardian * Female of child-bearing potential must have a negative pregnancy test at the beginning of the trial. If sexually active, they must have no intention of conceiving while on treatment with antirheumatic drugs. Exclusion Criteria: * \- Patients with systemic JIA according to ILAR criteria * Patients with undifferentiated arthritis according to ILAR criteria * Patients with severe disease-related ocular damage and who need systemic treatment for uveitis * Patients who received glucocorticoid treatment 3 months prior to baseline visit * Patients who had previously unsuccessfully attempted tapering cs/b/bs/tsDMARDs * Patients with severe damage as per caring physician measured * Prior or current history of other significant concomitant illness(es) that, according to the Investigator's judgment, would adversely affect the patient's participation in the study * Any other medical condition or laboratory examination which in the opinion of the caring physician should exclude the patient from participation to the study