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Effect of Omalizumab in the Skin of Food Allergy Patients
Sponsor: National Jewish Health
Summary
The goal of this interventional study is to evaluate whether skin barrier abnormalities occur in subjects with a food allergy, as determined by positive oral food challenge (OFC). The main question it aims to answer is whether these skin barrier abnormalities can be reversed by omalizumab. If there is a comparison group: Researchers will compare non-food allergic participants (who do not receive omalizumab) to see if they experience skin barrier abnormalities. All food allergic participants will receive 4 months of Omalizumab treatment as well as two Oral Food Challenges. Participants will all undergo skin barrier assessments.
Key Details
Gender
All
Age Range
1 Year - 55 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2024-10-01
Completion Date
2026-12
Last Updated
2025-05-02
Healthy Volunteers
Yes
Conditions
Interventions
Omalizumab Injection
Omalizumab is a monoclonal antibody FDA-approved for treatment of food allergy.