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NOT YET RECRUITING
NCT06619093

Relationship Between Biological Phenotype, Clinical Severity of Sickle Cell Disease, and Blood Coagulation

Sponsor: Hospices Civils de Lyon

View on ClinicalTrials.gov

Summary

Sickle cell disease is characterized by chronic hemolytic anemia and blood rheological alterations. In addition, blood coagulation abnormalities have been reported in patients with sickle cell disease and hemolysis-derived products could be involved. The investigators hypothesized that patients with sickle cell disease and severe hemolysis (Lactate Dehydrogenase level \> 484 IU/L) could have an increased risk of hypercoagulable state and subsequent thromboembolic complications.

Key Details

Gender

All

Age Range

8 Years - Any

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2025-02-01

Completion Date

2028-02-01

Last Updated

2025-01-15

Healthy Volunteers

No

Interventions

OTHER

blood sampling

3 additional citrate tubes (2.7mL)

Locations (2)

Insitut Hématologique et Oncologique Pédiatrique (IHOPe)

Lyon, France

Service de Médecine Interne - Hôpital Edouard Herriot

Lyon, France