Clinical Research Directory

Inclusion Criteria: * Voluntarily participate and have the subject and their legal guardian jointly sign the Informed Consent Form. * The age of the subjects is between 50 and 85 years old. * BMI≥19kg/m2 and ≤32.5 kg/m2, weight ≥45 kg and ≤100 kg at screening or baseline. Exclusion Criteria: * Cognitive impairment of subjects due to other medical or neurological factors (other than AD) * History of stroke or transient ischemic attack, seizures, or other unexplained loss of consciousness within the past year * With any mental illness that may interfere with the cognitive assessment of the subjects. * With history of moderate or severe renal dysfunction. * With Uncontrolled stable hypertension. * With history of severe trauma or major surgery in the 6 months prior to the screening period, or planned surgery during the study. * History of malignancy within 5 years prior to screening.