Clinical Research Directory
Browse clinical research sites, groups, and studies.
Dexmedetomidine in Reducing Postoperative Delirium in Cardiac Surgery Patients
Sponsor: Xijing Hospital
Summary
Delirium is a common consequence of cardiac surgery and associates with poor outcomes. Multiple causes can trigger delirium occurence, and it has been hypothesised that sleep disturbances can be one of them. Dexmedetomidine may be effective in reducing delirium. The aim of this study was to demonstrate preoperative dexmedetomidine nasal spray in cardiac surgery patients can reduce postoperative delirium by improving preoperative sleep.
Official title: Dexmedetomidine in Reducing Postoperative Delirium in Cardiac Surgery Patients：a Single-center, Double- Blind, Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
686
Start Date
2025-03-03
Completion Date
2027-03-30
Last Updated
2025-07-22
Healthy Volunteers
No
Interventions
Dexmedetomidine nasal spray
Participants will be randomised to receive either dexmedetomidine or saline nasal spray (1.5ug/kg, ideal body weight) at the night before surgery and 30 minutes before induction.
Locations (1)
Xijing Hospital
Xi'an, Shaanxi, China