Clinical Research Directory

Inclusion Criteria: * Age: 18 years and older. * Diagnosis: Diagnosed with coronary artery disease with native large vessel lesions confirmed by coronary angiography. * Treatment Plan: Scheduled to receive paclitaxel drug-coated balloon angioplasty. * Informed Consent: Patients have been fully informed about the nature and purpose of the study, and have voluntarily agreed to participate, with signed informed consent. * Physiological Status: Cardiac function classified as NYHA I-III. Exclusion Criteria: * Allergy History: Known allergies to paclitaxel or any materials used in angioplasty (e.g., contrast agents). * Severe Complications: Uncontrolled hypertension (systolic blood pressure \>180 mmHg or diastolic blood pressure \>110 mmHg). * Other Medical Conditions: Active bleeding or clotting disorders. * Other serious diseases with a life expectancy of less than 1 year (e.g., advanced cancer). * Pregnancy or Nursing: Women who are currently pregnant or breastfeeding. * Participation in Other Studies: Currently participating in other clinical trials that might affect the results of this study. * Psychological or Behavioral Factors: History of psychiatric or behavioral disorders that could interfere with adherence to study protocols, or communication barriers that prevent understanding of study requirements.