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Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery
Sponsor: Ain Shams University
Summary
The aim of this study is to evaluate the efficacy of intra-operative phentolamine vs intraoperative esmolol for hypotensive anesthesia in functional endoscopic sinus surgery.
Key Details
Gender
All
Age Range
21 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-10-10
Completion Date
2025-04-01
Last Updated
2024-10-01
Healthy Volunteers
No
Conditions
Interventions
Phentolamine
A loading dose of 1-5 mg IV bolus over 1 minute is given followed by an IV infusion of a rate of 0.1-2 mg/min according to patient desired target mean arterial pressure (MAP) 50-60 mmHg over a volume of 10ml
Esmolol
A loading dose of 1 mg/kg IV infused over 1 minute is given followed by an IV infusion of 0.15-0.3 mg/kg/min according to patient desired target mean arterial pressure (MAP) 50-60 mmHg over total volume of 10ml
Locations (1)
Ain Shams University
Cairo, Egypt