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ENROLLING BY INVITATION
NCT06621004
EARLY_PHASE1

Low Dose Magnesium Sulphate

Sponsor: Ain Shams University

View on ClinicalTrials.gov

Summary

This clinical trial aims to compare Patients who receive propranolol 1-2 mg to Patients who receive propranolol 1-2 mg in addition to magnesium sulphate infusion 10 mg/kg to see if IV magnesium can stability mean arterial blood pressure and heart rate in patients undergoing nasal surgeries as well as the quality of postoperative analgesia, degree of sedation mean arterial blood pressure and HR will be recorded intraoperative and Participants will be asked to rate the pain at the first, second, fourth, sixth and 24th postoperative hour using the VAS score. * Analgesic requirements: The time to first demand analgesia and the total amount of analgesia required in the 1st 24 will be recorded. * Sedation score: the degree of sedation will be assessed using the Ramsy sedation score

Official title: Low Dose Magnesium Sulphate in Nasal Surgery

Key Details

Gender

All

Age Range

20 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

130

Start Date

2024-08-25

Completion Date

2025-01-31

Last Updated

2024-10-09

Healthy Volunteers

No

Interventions

DRUG

Patients will receive propranolol 1-2 mg.

Patients will receive propranolol 1-2 mg. prepared in a 10 ml syringe (100 ug/ml).

DRUG

Patient receives magnesium sulphate

Magnesium sulphate 10%: 1g ampoule (10ml), will be prepared in a syringe pump to be given at a rate of 40 ml/hr . Another syringe of 10 ml 0.9% sodium chloride will be prepared to be given in group (P).

Locations (1)

Ain Shams University

Cairo, Egypt