Clinical Research Directory

Inclusion Criteria: * Age ≥ 18 years; * Patient operated for one anastomosis gastric bypass followed by Fundoplicature with stomach excluded for disabling gastroesophageal reflux requiring surgery within 2 years prior to inclusion; * Patient in failure of medical treatment; * Weight loss greater than 50% of excess weight; * Patient with preoperative objective investigations (gastrojejunal fibroscopy, ph-impedancemetry, abdominal CT scan) of gastroesophageal reflux disease; * Patient able to understand study-related information and to complete quality-of-life questionnaires in the opinion of the investigator; * Patient willing to accept study evaluations; * For women of childbearing age, effective contraception for the duration of the study or negative blood pregnancy test; * Patient has been informed and has given free, informed and written consent. Exclusion Criteria: * Patient with conversion from one anastomosis gastric bypass to Y bypass for disabling gastroesophageal reflux requiring surgery; * Patient with concomitant hiatal hernia correction for one anastomosis gastric bypass ; * Patient with secondary one anastomosis gastric bypass ; * Patient with a deregulated diet; * Patient under legal protection, or deprived of liberty by judicial or administrative decision; * Patient unable to understand study information for linguistic, psychological, cognitive or other reasons; * Women who are or may become pregnant, of childbearing age, without effective contraception or who are breast-feeding; * Patient participating in another clinical trial, or in a period of exclusion from another clinical trial that could interfere with the results of the present study; * Patient not covered by a social security scheme.