Clinical Research Directory

Inclusion Criteria: * Age 18-80 years, * Diagnosed with primary liver cancer (ICD-10: C22) (Referring to the diagnostic criteria in the "Primary Liver Cancer Diagnosis and Treatment Guidelines (2024 Edition)" and the "2024 CSCO Guidelines for the Diagnosis and Treatment of Biliary Malignancies), * Have not received any anti-tumor treatment (e.g., surgery, ablation, interventional therapy, radiotherapy, chemotherapy, targeted therapy, immunotherapy, etc), * Signed informed consent. Exclusion Criteria: * Have a history of other malignant tumors, * Have a history of other serious chronic diseases (e.g., heart failure, liver failure, kidney failure, etc.), * Expected survival time is no more than 3 months, * Severe physical or mental disability.