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Exploring How Viral Infections Affect People With Chronic Lung Disease
Sponsor: Imperial College London
Summary
Many people with chronic lung disease have disease flare-ups. It was previously believed that these were mainly caused by bacteria but recent evidence suggests that viruses could be an important trigger. This study will recruit volunteers with chronic lung disease and take samples both when well (at baseline) and during flare-ups (exacerbations) to better understand the role of viruses in triggering exacerbations and also how the immune response is affected. The researchers will follow the volunteers\' progress for up to two years. Whenever they get unwell they will take some samples (nose swabs, finger prick testing, phlegm sample) and post them to the researchers. Then, they will come in for a visit for more samples (blood tests, further swabs) and a review.
Official title: Prospective Cohort Study to Understand Impact of Viral Infection in Chronic Lung Disease
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
180
Start Date
2024-11-01
Completion Date
2027-04
Last Updated
2025-07-14
Healthy Volunteers
No
Conditions
Locations (1)
Royal Brompton Hospital
London, United Kingdom